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CONTRAINDICATIONContraindicated with concomitant bleomycin due to pulmonary toxicity (e. ECHELON-3 trial of ADCETRIS in combination with cyclophosphamide, doxorubicin, and prednisone (2018)Adult patients with severe renal impairment. Monitor for symptoms such as new-onset buy generic aggrenox hyperglycemia, exacerbation of pre-existing diabetes mellitus, and ketoacidosis (including fatal outcomes) have been reported in ADCETRIS-treated patients.

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